Announcing ICNMD 2022

The 17th International Congress of Neuromuscular Disease will take place July 5-July 9 in Brussels.

On Tuesday, we will have eight teaching courses and two hands-on courses (four hours each with a break in between).

The TC02 (TC02: Diagnosis and Treatment of GBS, CIDP and Autoimmune Nodopathies) & TC06 (Diagnosis of Inherited Neuropathies) are endorsed by the ICNMD/PNS Society

From Wednesday, the program includes a daily morning plenary followed by concurrent scientific sessions (22), workshops (12) and overarching sessions (11). Included are nine sessions for oral presentations and a special session for Regional Aspects of Neuromuscular Diseases – a joint WFN-ICNMD session.

Here are the titles of the four plenary sessions: 

Wednesday, July 6 | Trial Readiness and Advances in Therapy in Hereditary and Inflammatory Myopathies

Thursday, July 7 | The ALS-FTD Overlap Syndrome

Friday, July 8 | Guillain-Barré Syndrome: State of the Art and Challenges (Endorsed by ICNMD/PNS Society)

Saturday, July 9 | New Developments in Diagnosis and Treatment of Myasthenia Gravis and Congenital Myasthenic Syndrome

Here is the link to the preliminary program: https://icnmd.org/program2022/

For more information, contact Barbara Bricalli, program manager of ICNMD 2022 via www.icnmd.org. •

 

 

 

Neurosonology Specialty Group WFN Teaching Course

Meeting discussed use of transcranial Doppler ultrasonography as an essential daily modality in the critical-care setting.

By Marina Alpaidze, MD, PhD, Tsotne Samadashvili, MD, PhD, and Alex Razumovsky. PhD, FAHA, NVS

Conference room at Caucasus Medical Center.

The Neurosonology Specialty Group of the WFN is dedicated to the promotion of science and research as well of education and training in the field of ultrasonic techniques and its clinical utilization. Therefore, international cooperation and the dissemination of scientific information within the field of neurosonology is part of the WFN Neurosonology Specialty Group activities.

The WFN Neurosonology Specialty Group course considering clinical applications of transcranial Doppler (TCD) utilization in neurocritical care and neurosurgery was held Nov. 5, 2021, at the Caucasus Medical Centre in Tbilisi, Georgia. The meeting was conducted under the auspices of the NSG WFN, Georgian School of Anesthesia and Intensive Therapy, and Georgian Chapter of NSG WFN, and the Georgian Society of Cerebral Hemodynamics and Neurosonology.

Razumovsky (top left), L.Tsikarishvili. (bottom left), T. Samadashvili (top right), M. Alpaidze (bottom right).

Among the faculty were Drs. T. Samadashvili, MD, PhD, president of the Georgian School of Anesthesia and Intensive Therapy (NGO) and chair of the anesthesiology department at Caucasus Medical Centre; Lado Tsikarishvili, MD, PhD, chair of the neurosurgery department at Caucasus Medical Centre; M. Alpaidze, MD, PhD, professor in the department of radiology at the Tbilisi State Medical University; and Alexander Razumovsky, PhD, FAHA, NVS, secretary of the WFN Neurosonology Specialty Group.

(From left to the right) L. Tsikarishvili (neurosurgeon), T. Samadashvili (anesthesiologist), M. Alpaidze (radiologist), and A. Razumovsky (neurophysiologist).

This course was designed for different medical specialists, including neurologists, neurocritical care physicians, and neurosurgeons.  Presentations were related to the clinical yield of TCD for neurocritical care applications, specifically for patients after subarachnoid hemorrhage and traumatic brain injury. Different aspects of neurosurgical, critical care, and neurosonology were discussed in detail. Among them were management strategies of cerebral vasospasm after SAH and TBI. Some new trends in the clinical utilization of neurosonology applications were debated. Due to the COVID-19 regulations in Georgia, the meeting offered simultaneous live broadcast for a wide-ranging audience. •

Marina Alpaidze, MD, PhD, is professor in the radiology department at Tbilisi State Medical University. Tsotne Samadashvili, MD, PhD, is chair of the anesthesiology department at Caucasus Medical Center. Alex Razumovsky. PhD, FAHA, NVS, is secretary of the Neurosonology Specialty Group of the WFN.

 

 

American Epilepsy Society Announces Position Statement on Valproate Use in Women of Childbearing Potential

R. Edward Hogan, MD, David G. Vossler, MD

The American Epilepsy Society (AES) president, R. Edward Hogan, MD, recently shared important information about the serious risks associated with use of valproate (valproic acid, divalproex) by women of childbearing potential, as highlighted in the updated AES Position Statement on the Use of Valproate by Women of Childbearing Potential.

Valproate is prescribed across a diverse range of specialties and is approved by the U.S. Food and Drug Administration (FDA) for treatment of epilepsy and bipolar disorder and for migraine headache prophylaxis.

The updated AES position statement highlights specific warnings related to significant risk of fetal teratogenicity and risk of decreased IQ and other neurodevelopmental disorders, including autism, in children exposed to valproate in utero, and a contraindication to its use for migraine prevention in pregnant women and women of childbearing potential not using effective contraception.

The statement cites evidence that increased awareness of these important considerations for women of childbearing potential correlates to reduced fetal exposure and risks. Based on this evidence and the epilepsy care experience, AES encourages provider conversations with patients to mitigate these risks, reduce in utero valproate exposure, and promote safe and effective treatment for women of childbearing potential.

AES Council on Clinical Activities Chair David G. Vossler, MD, cited this AES position statement as an important extension of the ongoing work of the Council’s Treatments Committee to monitor and inform AES members about important Drug News and FDA Alerts related to care of people with epilepsy. •

 

 

Dr. Paul Kleihues (May 21,1936-March 17, 2022)

Dr. Paul Kleihues passed away March 17, 2022, at the age of 85 years.

Dr. Kleihues was a world-renowned neuropathologist in the field of brain tumor research. Starting his scientific and professional career at neuroscience and neuropathology institutions in Germany, he later served as director of the Institute of Neuropathology at the university hospital in Zurich, and subsequently as head of the International Agency for Research on Cancer (IARC), World Health Organization (WHO). He took responsibility for the WHO classification of human tumors, and was particularly interested in the integration of clinics, radiology, histology, and molecular genetics as fundamental basis for comprehensive and precise tumor typing. His personal professional and scientific activities, in tight cooperation with Dr. Hiroko Ohgaki, left a sustainable legacy in brain tumor classification.

Within the international neuropathology community, Dr. Kleihues was a highly appreciated and benevolent mentor, colleague, and friend.

The IARC commemorates Dr. Kleihues and his achievements in a respectful and compassionate obituary: https://www.iarc.who.int/news-events/dr-paul-kleihues-21-may-1936-17-march-2022/ •

—Dr. Johannes Hainfellner

Division of Neuropathology and Neurochemistry (Obersteiner Institute) Department of Neurology Medical University of Vienna, Austria

2022 WFN Grants-In-Aid

The WFN mission is to foster quality neurology and brain health worldwide, and this year, the WFN is offering up to six grants of up to $25,000 with a maximum spend of $100,000.

Research projects that will be considered for funding include:

  • Education such as research on neurological education and patient education (Please note that grants related to the funding or creation of neurological residency or fellowship training programs will not be awarded.)Improvement of neurological services
  • Regional collaboration
  • Disease-based projects (Please note that pure laboratory or “bench research” projects are out of the scope of this grant program.)

2022 grant applications that are likely not to be adversely impacted by the COVID-19 pandemic will be preferred.

We look forward to reviewing applications for the 2022 WFN grant program.

Eligibility

Neurologists less than 10 years from graduating in neurology from WFN Member Societies.

Preference will be given to applicants residing in areas of World Bank low/lower-middle-income countries.

Aim

The WFN seeks to fund low-cost, high-impact education and outcome research projects able to be implemented locally (at source). International cooperation is encouraged.

(Please note projects to provide routine health care and ongoing research proposals are not eligible).

Criteria

Projects should be in education, improvement of services (regional or national), or scientific and require the collection of data to test a hypothesis.

Each grant will have to satisfy its terms of the agreement. (See below.)

In the application, please address the following points:

  • Relevance: How does the project directly address the mission of the WFN?
  • Value: What is the return on invested effort in funds and/or time?
  • Viability: Is this a time-limited project with a measurable outcome or is it an initiative that will grow and support the development of further research or initiatives?
  • Synergy: Within the WFN and among committees, initiatives, and task forces, with outside partners, governmental and non-governmental organisations, the WHO, fundraising agencies etc.
  • Please suggest possible partners. For example, a project on stroke would probably be interesting for the WSO, for epilepsy possibly with the ILAE, etc. (See co-sponsored grants.)
  • Evaluation: How will the outcome be measured?
  • Management: Good governance, transparent monitoring, and clear interim and financial reports are required.

Co-Sponsored Grants

The WFN encourages co-sponsored grants. These grants will be co-sponsored by the WFN and a partner organization. The partner organization can be a scientific society (e.g. ILAE, MDS, etc.), a regional society (EAN, AOAN etc.), or a national society. The partner organization will sign a sponsorship agreement with the WFN to define the shared costs and the role of the individual partners in such projects.

Project responsibility and reporting will be shared by the WFN and the partner organization.

Deadlines

  • Application due by July 1, 2022
  • Applicants will be notified of successful funding in due course after the closing date.
  • Once applicants are informed of the decision, funding will begin as soon as it can be arranged thereafter.
  • Applications are to be submitted exclusively using the online WFN grant application form and should include the following:

Application Checklist

  • The name of the lead applicant with curriculum vitae and any sponsoring group
  • Title of the project
  • Description of the project
  • Direct relevance of the project to the mission of the WFN
  • Viability of the project
  • Timeline of the project, dates, and duration
  • Detailed budget in U.S. dollars
  • Name of bank to enable electronic funds transfer and confirmation of the same by the specified bank
  • Approval by a local or institutional ethics committee

All funding must be received through an academic institution account.

Please visit the WFN website for additional information. •

The WFN: Past and Future

Wolfgang Grisold

This is my first column as the WFN president in World Neurology but not my first article in our newsletter, edited by Steven Lewis. World Neurology has become an important source of information for members and serves to communicate information on the WFN.

Before I comment on the present state of the WFN, and the vision for this year and the following years, I want to thank the outgoing president, William Carroll, and all trustees having served in the previous administration, for their huge efforts and devotion to the WFN.

I also want to thank all committees, Specialty Groups, cooperating societies, and the WFN office as well as the professional conference organizer (PCO) (Kenes) who mastered the difficult transition from classic congress to virtual congresses.

Ryuji Kaji, the outgoing vice president, was chair of this successful transition into a virtual congress. The abilities of the PCO also must be commended.

The WFN is a U.K. charity with 123 member societies. The work is supported by the London office, a few external coworkers, and a lean structure.

The WFN is by constitution and voting system in a constant flux in leadership. This year, one new trustee position and a new secretary general will be at disposition at the next Congress of Delegates (COD) meeting and adds to the dynamic effects of change.

The WFN has a robust and detailed structure, which serves as the basis for further improvement and development. This transition of administration will be smooth, and the main targets and goals will be adapted and improved.

In the first Trustee meeting, held Jan. 13, 2022, Prof. Guy Rouleau (Canada) was welcomed into the WFN board of trustees as the new vice president. Prof. Rouleau is from Montreal, Canada, was the delegate of Canada to the WFN, has participated in the WFN department visit program, and is the Congress president for the World Congress of Neurology (WCN) 2023 in Montreal.

The trustees decided on the composition of the WFN leadership until the next COD meeting 2022. The position of the secretary general will be taken by Steven Lewis (U.S.), who has been a long-time supporter within the leadership. We decided to use the opportunity and allow more regional representation, which will include Prof. Chandrashekhar Meshram (India), Prof. Marco Medina (Honduras), and Prof. Riadh Gouider (Tunisia) from the Asian, Latin American, African, and the Pan-Arab regions, respectively.

This is a unique opportunity to have representatives of the regions on the board, and gives the trustees the flexibility to have this option until the next COD meeting, where the election of one trustee and secretary general will take place, and the further composition of the coopted trustees can be adjusted again, within the available positions.

Due to COVID-19 and travel conditions, a traditional first face-to-face meeting with the trustees and the regions was not possible this year. COVID hampers activities on the one hand, and on the other, shows what creative potential this provides to communication, teaching, and virtual congresses. This will be overcome by a 2-day virtual conference, which will give each region and the trustees the possibilities to learn more on the needs of neurology worldwide.

At this time, most terms of office for the committees come to an end, and much effort will be exercised to select the most interested and capable persons as well as to selecting regions and gender.

For the upcoming year, there is still uncertainty on the possibility of live meetings, but it is planned that the WFN leadership will meet with the leadership of the AAN and the EAN this year, at this year’s conferences. Hopefully, it will be possible to also attend the Indian Academy of Neurology and the Asian Oceanian Congress of Neurology meetings, and the WFN will also attend other regional meetings. The annual COD meeting will be this fall, although the site has not yet been determined.

WCN

One important task of the WFN is the organization of biennial congresses, rotating through the regions. After the successful congress with SIN 2021, which was virtual, the next congress is planned for 2023 in Montreal hosted by the Canadian society, and in 2025 in Seoul, Korea.

For both meetings the preparations at different levels are ongoing, and the first congress announcements and calls for Montreal will be appearing soon.

The WCN is an important part of the WFN activities and provides attractive programs with plenary sessions showcasing new and current developments, scientific sessions aimed at specific topics, a large number of abstract presentations, and general education. The WCN aims at high scientific quality and universal approach for many regions as well as communicative aspects between participants and members.

We will aim to have a patient day and will support the activities of young neurologists. For countries in need, adapted fees will be in place according to the income status, and congress bursaries will be available. As lessons learned from the pandemic, we will also provide hybrid activities featuring important topics.

World Brain Day

The WFN has created the World Brain Day (WBD), which has become an important and powerful instrument to facilitate topics and neurological issues globally. This year’s topic will be Brain Health for All, which will put us in contact with many regional societies, as well as reflects the importance of the topic that was started by the WFN last year on the initiative of our Past-President William Carroll. At this stage, the content was composed of videos and webinars that were well received and also stimulated the interest in this topic.

This year, we will work closely with the regions and will enhance our efforts to encourage local and regional events. Visit the WFN website for further developments and try to implement brain health initiatives in your region. As in previous years, we will provide tools, such as posters, press statements, and other useful support that can be adapted and used locally to celebrate WBD.

WHO

From the ongoing activities of brain health and WBD, the close cooperation with the WHO will continue to globally raise the awareness for neurology and provide more access for those in need. The WFN has contributed jointly with the Global Neurology Alliance (GNA) to develop comments and suggestions for the Intersectorial Global Action Plan (IGAP), and the WFN considers this an important step for the global development of neurology.

Traditionally, the WFN has been in close contact with the WHO, such as the involvement in the ICD, the joint publication of the Atlas (Editions 1 and 2) and historically a “white book” (Country Resources for Neurological Disorders) on neurological resources, which dates back to 2006 and needs a relaunch.

The WFN also collaborates in WHO activities related to the COVID pandemic and is engaged in several workforces.

It will be important for the regional societies to engage in local WHO activities as this has been done previously by some regions. This will deal with specific topics and can also increase awareness and possibly impact.

Closely linked with this global activity is the Needs Registry. Looking at needs, the outgoing president, Prof. Carroll, on behalf of the WFN, will finalize a Needs Registry, which is based on a membership survey, and will give more details on the worldwide needs. This important paper will be published on behalf of the WFN and will be of help to better understand neurologic needs and access worldwide.

Education

Education is one of the core missions of the WFN. Education at all levels will be one of our main tasks.

We have a spectrum of educational activities, ranging from the Junior Traveling Fellowships and congress bursaries, to WFN Teaching Centers and Department Visits. Also, educational sessions are part of the WCN. We have an educational day in Africa, a joint headache educational day with the International Headache Society and the Global Patient Advocacy Coalition

(GPAC) and the annual Regional Teaching Course in Africa with the EAN. These activities will be continued and updated. (For details, visit the WFN website). The educational days in Africa have become a good template to reach a large audience, and these educational days can be expanded to other regions. The education day on headache with IHS/GPAC will be continued this year.

We will increase our activities in e-learning, and the e-learning hub on the WFN website, which was introduced last year, and will be expanded. We look forward to seeing how this important instrument will contribute to global educational activities.

We are also determined to look at new educational activities, such as mentorship, advocacy, and leadership. Format hybrid meetings and asynchronous meetings will be considered. New models, such as apps, mini or micro learning, as well as the concept of M (mobile) learning will be evaluated for possible use.

Core Curriculum

The definition of neurology as a field is difficult. Even more difficult to define is the content of a core curriculum. This is due to the large variation of the resources of our membership, which ranges from highest standards toward members with hardly any neurological workforce. Discussions within the WFN on a possible core curriculum have been ongoing for years. Interviews with several members have shown that a basic core curriculum will be important for many members societies to develop neurology and neurological facilities.

For the development of future programs, we will also receive input from the specialty groups and the Global Neurology Alliance, which is composed of world societies, specialist societies, the regions, and specialty groups.

In previous years, this cooperation has been effective and adds to the impact of programs. A good example is the Regional Teaching Course in Africa, which is chaired by the EAN and where the AAN, the International Brain Research Organization (IBRO), and the WFN regularly participate. We are grateful to the educational activities of the specialty groups. As an example, at this year’s International Congress of Neuromuscular Disease (https://icnmd.org), a joint WFN-ICNMD lecturer will illustrate the topic of neuromuscular disease in lower middle-income countries.

The content of education is not limited to knowledge and science. We also need to teach advocacy and leadership for neurologists. We must find ways to help our young and trained neurologists find attractive positions and work in and for the WFN.

Our vision is that successful participants of our leadership seminars will be able to participate in the work of committees and leadership and be able to learn and see the organizational needs and requirements.

The WFN has a grant award program with yearly funding. This will be continued and will be mainly directed toward educational activities in both research and practical application.

Publications

The WFN has three publications: the Journal of the Neurological Sciences (John England, Editor), eNS (Walter Struhal, Editor) and World Neurology (Steven Lewis, Editor). These publications help to promote neurology worldwide and are an important source of information and education. We have now established a platform for recommendations from the editors, and hope to be able to synchronize on important topics in the future

Social media is helping to promote new articles and important developments and has become an important part of our communication. The content and targets will need to expand to a larger group, including lay persons, patients, and health care providers.

Internal Work

Based on the WFN structure, we need to improve communication and outreach with regions and member societies. The detailed work with the members societies from last year has increased our understanding and identified some blind spots, which need to be removed.

Internally, the WFN needs to be prepared for the future. In addition to gender, young neurologists, and patients, we will make sure the future transitions of administrations will be smooth and already incorporate the president-elect, which will need a change of the procedures.

Importantly, we will need to consider gender and diversity, the need of young neurologists, and install a platform for patient organizations into the WFN. This will need preparatory work and will require important input from our committees, which will be asked to provide ideas and suggestions.

This work needs strong administrative support from the trustees and organizationally from the office team, which is an important part of our strategy.

In Summary

Communication, increasing the impact of the WFN, and internal adaptations will be the task for the WFN in the next period, and I will use this platform to update and inform on the recent developments.

Despite our own personal regional background and regional interests, we have to strive for a cosmopolitan approach, which by etymology would be best described as “citizens of the world” and describes the spirit of the WFN’s approach.

I look forward serving as the WFN president and building on our robust structure to consolidate and improve the present structures and to encourage and work on future projects. •

 

Email me with your ideas, suggestions and comments: wolfgang.grisold@wfneurology.org

Coma and Disorders of Consciousness Specialty Group

Call for Chair Position

The WFN Specialty Group on Coma and Disorders of Consciousness is an important part of the Specialty Groups of the WFN.

We are looking for a new chair for this position, and we encourage you to send us your interest and qualifications. The basic condition is that you are a neurologist and come from a country that is a WFN member society. Your applications will be reviewed by a committee, and the region where you come from will be asked for advice. The WFN will make a final decision, and there will be no further elaboration on the decision.

The position will be for two years, renewable once, and is not remunerated. The task is to identify and bring in the most current aspects of this field and suggest topics and educational activities for the WCN.

For information on the other WFN Specialty Groups, visit the WFN website.

If you are interested, please send: why you are interested and why you are qualified a brief CV present experience.

Address correspondence to: Wolfgang Grisold, President, WFN; c/o laura@wfneurology.org.

Letter from the editors

Welcome to the January-February 2022 issue of World Neurology.

Steven L. Lewis, MD, Walter Struhal, MD

The issue begins with the President’s Column, where new WFN President Wolfgang Grisold discusses the past, present, and future of the WFN as well as many activities and goals currently planned under his presidency. This report is also followed by an announcement and photos of all of the new WFN trustees.

Dr. Arina Tamborska announces an ongoing survey of neurologic complications of COVID-19 from the University of Liverpool with support from the World Health Organization (WHO) and the World Federation of Neurology (WFN).

In this issue’s column about the WFN Committees and Specialty Groups, edited by WFN President Wolfgang Grisold, the activities of the WFN Education Committee and the WFN Environmental Neurology Specialty Group are highlighted. This issue also includes a call for a new chair for the WFN Coma and Disorders of Consciousness Specialty Group.

In the History Column, Dr. Peter Koehler discusses the history of insulin coma therapy (ICT) and its historical role as a treatment for neuropsychiatric disease and the observations of the neurological signs induced by this procedure.

Dr. Gaminit Pathirana, president of the Association of Sri Lankan Neurologists (ASN), reports on the history and activities of the ASN, which includes its recent and successful meeting.

In the WFN Training Center report, Dr. Ndayisenga Arlène provides a wonderful report of her WFN-sponsored full neurology training at the WFN Training Center at the Cheikh Anta Diop University in Senegal, where she is the first fully trained neurologist to graduate as a WFN-sponsored trainee from this center. She has now successfully returned to Rwanda as the fifth neurologist in that country.

Dr. Tissa Wijeratne provides a brief history of World Brain Day and the success of World Brain Day 2021 devoted to multiple sclerosis. The theme for this year’s World Brain Day 2022 is also announced in this issue and is devoted to Brain Health for All.

As always, we would like to thank all readers for their interest in World Neurology and invite ideas for contributions to be sent to Dr. Lewis or Dr. Struhal •

How Do You Diagnose COVID-19 Patients With Neurological Complications?

Call for Survey Respondents

By Dr. Arina Tamborska

Arina Tamborska

Researchers with the Global COVID Neurology Survey are calling on clinicians to help them better understand how neurological complications of COVID-19 are diagnosed around the world.

The project is being led by the University of Liverpool with support from the World Health Organization (WHO) and the World Federation of Neurology (WFN).

“We need clinicians around the world to share their experiences of how they diagnose neurological and neuropsychiatric syndromes and perceive their association with COVID-19,” said Dr. Arina Tamborska, NIHR academic clinical fellow in neurology at the University of Liverpool. “Your responses will play a role in the validation of a prospective WHO clinical record form, which will then be made openly available to everyone following the study’s completion.”

The survey will take up to 30 minutes to complete and involves questions about your clinical experience and several short case scenarios, describing patients with neurological complications as a result of COVID-19.

Participants will be named as a collaborator in any publications arising from the survey. All clinicians who treat patients with COVID-19 are eligible to participate, including trainees.

“Whether you are a neurologist or any other health care professional involved in the care of COVID-19 patients, your help would be greatly appreciated with this study, which we hope will lead to better treatments and outcomes for patients,” said Dr. Benedict Michael, senior clinician scientist fellow at the University of Liverpool.

Visit https://redcap.link/covidneurosurvey to take part. •

Dr. Arina Tamborska is a NIHR academic clinical fellow in neurology, brain infections group at the University of Liverpool, The Walton Centre NHS Foundation Trust, Liverpool, U.K.

Announcement of New WFN Trustees

Congratulations to the new WFN trustees.

The roles and responsibilities of the WFN trustees are expansive and include everything from creating educational programs, to planning the biennial World Congress and overseeing all WFN charity and fiduciary responsibilities.

The new trustees all bring unique skills and experience as well as perspectives from their regions to the trustee discussions and deliberations that will help guide WFN in the future.

We are pleased to have these leaders join the WFN trustees and are certain they will have a positive impact on improving the quality of the WFN’s activities to promote quality neurology and brain health worldwide. •